1 Result for "

137927-14-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "137927-14-1" in MCE Product Catalog:

Cat. No.: HY-105015
CAS No.: 137927-14-1
Target:  

Na+/K+ ATPase

Research Areas:  

Inflammation/Immunology

TY-11345 is an orally active gastric mucosal H +/K +-ATPase inhibitor, with IC50 values of 5.8 μM (Reference 1) and 3.3 μM (Reference 2) at pH 6.0, respectively. TY-11345 inhibits basal gastric acid secretion stimulated by Tetragastrin (HY-125556) and Pentagastrin (HY-A0261), and prevents gastric and duodenal injuries in rats. TY-11345 can be used in the research of peptic ulcer disease and acid-related gastrointestinal diseases .
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