1 Result for "

1396397-03-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1396397-03-7" in MCE Product Catalog:

Cat. No.: HY-124388
CAS No.: 1396397-03-7
Research Areas:  

Inflammation/Immunology

PDE4-IN-20 is a selective submicromolar phosphodiesterase-4 (PDE4) inhibitor with anti-TNF-α properties. PDE4-IN-20 exhibits significant biological activity in vitro and in vivo. The mechanism of action of PDE4-IN-20 is supported by molecular modeling studies, which reveal its binding mode with PDE4. PDE4-IN-20 was optimized in further conformational analysis and showed pharmacological characteristics similar to those of known PDE4 inhibitors .
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