1 Result for "

1404436-51-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1404436-51-6" in MCE Product Catalog:

Cat. No.: HY-108944
CAS No.: 1404436-51-6
Purity:  99.82%
Target:  

SHP2 SHP1 Phosphatase

Research Areas:  

Inflammation/Immunology

LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 (IC50=5 μM) and SHP2 (IC50=2.5 μM). LYP-IN-1 exhibits highly efficacious cellular activity in T- and mast cells. LYP-IN-1 can be used for the study of autoimmune disorders . LYP-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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