2 Results for "

142796-21-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "142796-21-2" in MCE Product Catalog:

2
Isosilybin A
Isosilybin A
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2 Cited Publications
Cat. No.: HY-N7043
CAS No.: 142796-21-2
Category:  

Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Glycine soya Flavonoids Phenols Polyphenols Disease Research Fields Cancer

Target:  

Apoptosis PPAR NF-κB p38 MAPK ERK Androgen Receptor

Isosilybin A is a PPARγ agonist that can be isolated from silymarin. Isosilybin A activates extrinsic and intrinsic pathways of apoptosis through targeting of the Akt-NF-kB-AR axis. Isosilybin A can relieve the inflammatory response in the rosacea model via inhibiting Erk and p38 signaling pathways and M1 macrophage polarization, with its targets related to RELA and VEGFA. Isosilybin A has anti-prostate cancer (PCA) activity [1][2][3].
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Isosilybin A (Standard)
Isosilybin A (Standard)
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Cat. No.: HY-N7043R
CAS No.: 142796-21-2
Category:  

Flavanonols Glycine soya Flavonoids Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae

Target:  

Reference Standards Apoptosis PPAR NF-κB p38 MAPK ERK Androgen Receptor

Isosilybin A (Standard) is the analytical standard of Isosilybin A (HY-N7043). Isosilybin A is a PPARγ agonist that can be isolated from silymarin. Isosilybin A activates extrinsic and intrinsic pathways of apoptosis through targeting of the Akt-NF-kB-AR axis. Isosilybin A can relieve the inflammatory response in the rosacea model via inhibiting Erk and p38 signaling pathways and M1 macrophage polarization, with its targets related to RELA and VEGFA. Isosilybin A has anti-prostate cancer (PCA) activity [1][2][3].
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