1 Result for "

1438242-59-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1438242-59-1" in MCE Product Catalog:

Cat. No.: HY-148961
CAS No.: 1438242-59-1
Target:  

mAChR ERK

Research Areas:  

Neurological Disease

HTL-9936 is an orally active partial agonist of muscarinic M1 receptor. HTL-9936 has an EC50 of 32 nM for human M1 receptor and an EC50 of 224 nM for human M4 receptor. HTL-9936 activates Gq/11 coupling, promotes inositol phosphate accumulation, ERK1/2 phosphorylation, β-arrestin recruitment and receptor internalization. HTL-9936 can be used in the research of Alzheimer's disease and schizophrenia .
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