1 Result for "

1613078-24-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1613078-24-2" in MCE Product Catalog:

Cat. No.: HY-123656
CAS No.: 1613078-24-2
Target:  

Apoptosis

Research Areas:  

Cancer

Antiproliferative agent-61 is a synthetic β-carlinyl chalcone with significant antiproliferative activity. Antiproliferative agent-61 showed significant effects in a range of solid tumor cell lines, with the most prominent effects in breast cancer. Antiproliferative agent-61 showed IC50 values of 2.25 and 3.29 μM in the human breast cancer MCF-7 cell line. Antiproliferative agent-61 significantly induced DNA fragmentation and apoptosis in breast cancer cells. Antiproliferative agent-61 inhibited the interaction of MDM2 with p53 and promoted the degradation of MDM2 .
loading...
    loading...