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Antiproliferative agent-61

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Antiproliferative agent-61 is a synthetic β-carlinyl chalcone with significant antiproliferative activity. Antiproliferative agent-61 showed significant effects in a range of solid tumor cell lines, with the most prominent effects in breast cancer. Antiproliferative agent-61 showed IC50 values of 2.25 and 3.29 μM in the human breast cancer MCF-7 cell line. Antiproliferative agent-61 significantly induced DNA fragmentation and apoptosis in breast cancer cells. Antiproliferative agent-61 inhibited the interaction of MDM2 with p53 and promoted the degradation of MDM2.

For research use only. We do not sell to patients.

  • Purity: 98.93%
  • CAS No.: 1613078-24-2
  • Formula: C22H18N2O3
  • Molecular Weight:358.39
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Antiproliferative agent-61 Chemical Structure
    Antiproliferative agent-61 Chemical Structure
CAS No.: 1613078-24-2
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Antiproliferative agent-61 Chemical Structure
    Antiproliferative agent-61 Chemical Structure
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