1 Result for "

1642300-52-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1642300-52-4" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-100423
CAS No.: 1642300-52-4
Purity:  99.79%
Synonyms: KPT-8602
Target:  

CRM1

Research Areas:  

Cancer

Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines .
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