1 Result for "

1918238-72-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1918238-72-8" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100849
CAS No.: 1918238-72-8
Target:  

JAK

Research Areas:  

Inflammation/Immunology

JAK3i is a highly selective JAK3 inhibitor (IC50: 0.43 nM). JAK3i forms a covalent bond with a cysteine in JAK3, but not the closely related kinase domains in JAK1, JAK2, or TYK2. JAK3i abolishes IL-2-driven T-cell proliferation in vivo and has the potential for  autoimmune disease research .
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