1 Result for "

195881-94-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "195881-94-8" in MCE Product Catalog:

Cat. No.: HY-13289B
CAS No.: 195881-94-8
Synonyms: (R)-SYN117 hydrochloride; (R)-RS-25560-197 hydrochloride; RS-25560-198 hydrochloride
Research Areas:  

Cardiovascular Disease

(R)-Nepicastat hydrochloride is the isomer of Nepicastat (HY-13289). Nepicastat (SYN117) is a selective,potent,and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .
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