1 Result for "

205678-26-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "205678-26-8" in MCE Product Catalog:

Cat. No.: HY-19306
CAS No.: 205678-26-8
Target:  

Integrin

Research Areas:  

Cancer

SB-267268 is a selective and nonpeptidic alpha(v)beta3 (αvβ3) and alpha(v)beta5 (αvβ5) integrins antagonist, with Kis of 0.9, 0.5 and 0.7 nM for human αvβ3, monkey αvβ3 and human αvβ5, respectively. SB-267268 inhibits human and mouse αvβ3 with IC50s of 0.68 and 0.29 nM, respectively. SB-267268 reduces angiogenesis and VEGF expression .
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