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2209854-03-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2209854-03-3" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P10769
CAS No.: 2209854-03-3
Target:  

AMPK Apoptosis

Research Areas:  

Metabolic Disease

MOTS-c (mouse) is a mitochondrial-derived polypeptide that can be used to regulates pancreatic cell function. MOTS-c (mouse) reduces insulin secretion and expression in INS-1E cells, and enhances glucagon secretion and expression in αTC-1 cells. MOTS-c (mouse) decreases the apoptosis in INS-1E and αTC-1. MOTS-c (mouse) counteracts diet-induced obesity and insulin resistance through AMPK activation .
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