1 Result for "

2230777-09-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2230777-09-8" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-N4208
CAS No.: 2230777-09-8
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Taccalonolide AJ is a microtubule stabilizer and antiproliferative agent with an IC50 of 4.2 nM against β-tubulin (β-tubulin) D226. Taccalonolide AJ increases cellular microtubule density, induces microtubule bundling, triggers G2/M cell cycle arrest with abnormal mitotic spindles, and inhibits cancer cell proliferation. Taccalonolide AJ can be used in the research of oral cancer, breast cancer, solid tumors, as well as tumors resistant to Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A) .
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