Taccalonolide AJ
Based on 1 publication(s) in Google Scholar
Taccalonolide AJ is a semi-synthesis compound with cellular microtubule stabilizing activity. Taccalonolide AJ exhibits high potency antiproliferative activity against cancer cells, with an IC50 of 4.2 nM for HeLa cells.
For research use only. We do not sell to patients.
- Purity: 98.6%
- CAS No.: 2230777-09-8
- Formula: C34H44O14
- Molecular Weight:676.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Taccalonolide AJ
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Biological Activity
microtubule[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.0042 μM
Compound: Taccalonolide AJ
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Antiproliferative activity against human HeLa cells by SRB assay
Antiproliferative activity against human HeLa cells by SRB assay
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[PMID: 24491636] |
| HeLa | IC50 |
4.2 nM
Compound: 4
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Antiproliferative activity against human HeLa cells by SRB assay
Antiproliferative activity against human HeLa cells by SRB assay
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[PMID: 24959756] |
| HeLa | IC50 |
4.2 nM
Compound: Taccalonolide AJ
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Antiproliferative activity against human HeLa cells
Antiproliferative activity against human HeLa cells
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[PMID: 23855953] |
Chemical Information
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CAS No. 2230777-09-8
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Appearance Solid
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Molecular Weight 676.70
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Formula C34H44O14
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Color White to off-white
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SMILES
C[C@]1([C@@]2(O)C)[C@]3(OC2=O)[C@H]([C@@H](C)[C@@]4([H])[C@@]1([H])[C@@H]([C@]5([H])[C@@]4([C@H]([C@@H](OC(C)=O)[C@@]6([H])[C@@]5([H])[C@H](C([C@]7([H])[C@@]6([C@H]([C@@H](O8)[C@@H]8C7)OC(C)=O)C)=O)O)OC(C)=O)C)O)O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 110 mg/mL (162.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4778 mL | 7.3888 mL | 14.7776 mL | 36.9440 mL |
| 5 mM | 0.2956 mL | 1.4778 mL | 2.9555 mL | 7.3888 mL | |
| 10 mM | 0.1478 mL | 0.7389 mL | 1.4778 mL | 3.6944 mL | |
| 15 mM | 0.0985 mL | 0.4926 mL | 0.9852 mL | 2.4629 mL | |
| 20 mM | 0.0739 mL | 0.3694 mL | 0.7389 mL | 1.8472 mL | |
| 25 mM | 0.0591 mL | 0.2956 mL | 0.5911 mL | 1.4778 mL | |
| 30 mM | 0.0493 mL | 0.2463 mL | 0.4926 mL | 1.2315 mL | |
| 40 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9236 mL | |
| 50 mM | 0.0296 mL | 0.1478 mL | 0.2956 mL | 0.7389 mL | |
| 60 mM | 0.0246 mL | 0.1231 mL | 0.2463 mL | 0.6157 mL | |
| 80 mM | 0.0185 mL | 0.0924 mL | 0.1847 mL | 0.4618 mL | |
| 100 mM | 0.0148 mL | 0.0739 mL | 0.1478 mL | 0.3694 mL |
Taccalonolide AJ Related Classifications
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