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2244895-42-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2244895-42-7" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-128661
CAS No.: 2244895-42-7
Purity:  99.40%
Research Areas:  

Metabolic Disease

IDH1 Inhibitor 2 (compound 13) is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development .
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