1 Result for "

2250025-94-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2250025-94-4" in MCE Product Catalog:

Cat. No.: HY-136258
CAS No.: 2250025-94-4
Target:  

nAChR

Research Areas:  

Neurological Disease

nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) of nAChR containing a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of (α4)3(β2)2 nAChR to ACh (10 µM) with an EC50 of 0.26 µM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity .
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