1 Result for "

2365172-42-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2365172-42-3" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-130604
CAS No.: 2365172-42-3
Purity:  99.61%
Research Areas:  

Inflammation/Immunology Cancer

DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets .
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