1 Result for "

2370013-12-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2370013-12-8" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-132842
CAS No.: 2370013-12-8
Purity:  99.71%
Synonyms: DZD9008
Target:  

EGFR Btk

Research Areas:  

Cancer

Sunvozertinib (DZD9008) is a potent ErbBs (EGFR, Her2, especially mutant forms) and BTK inhibitor. Sunvozertinib shows IC50s of 20.4, 20.4, 1.1, 7.5, and 80.4 nM for EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and Her2 Exon20 YVMA, and EGFR WT A431, respectively (patent WO2019149164A1, example 52) .
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