1 Result for "

2382768-62-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2382768-62-7" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-132168
CAS No.: 2382768-62-7
Purity:  99.94%
Target:  

mTOR

Research Areas:  

Cancer

RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity .
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