1 Result for "

2410384-50-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2410384-50-6" in MCE Product Catalog:

Cat. No.: HY-146294
CAS No.: 2410384-50-6
Target:  

COX

Research Areas:  

Inflammation/Immunology

COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively .
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