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2429877-30-3

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Cat. No.: HY-129603
CAS No.: 2429877-30-3
Purity:  98.96%
Research Areas:  

Cancer

SI-109 is a potent STAT3 SH2 domain inhibitor (Ki=9 nM) with antitumor activity. SI-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). SI-109 and an analog of CRBN ligand lenalidomide have been used to design PROTAC STAT3 degrader SD-36 .
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