1 Result for "

2436544-27-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2436544-27-1" in MCE Product Catalog:

Cat. No.: HY-128522
CAS No.: 2436544-27-1
Purity:  99.59%
Target:  

Ras

Research Areas:  

Cancer

ARS-1323-alkyne is a covalent inhibitor probe that covalently binds to the Switch-II pocket (S-IIP) of the KRAS G12C mutant protein. ARS-1323-alkyne visualizes the covalent modification of KRAS G12C and quantitatively measures the binding efficiency of the inhibitor to the target. ARS-1323-alkyne can be used to validate the target occupancy of KRAS G12C inhibitors and the synergistic mechanism of combination therapy .
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