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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
25+ohc
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "25+ohc" in MCE Product Catalog:
31
Target:
4
Target:
1
1 Cited Publications
Synonyms: GPR183 antagonist-1
Target:
Research Areas:
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice .
Synonyms: 25-OHC-d6
Cat. No.: HY-113962S
CAS No.: 2260669-11-0
Synonyms: 7α,25-OHC-d6
Cat. No.: HY-113134R
CAS No.: 2140-46-7
Synonyms: 25-OHC (Standard)
Category:
Cat. No.: HY-133974
CAS No.: 64907-23-9
Synonyms: 7-keto-25-OHC
7-keto-25-Hydroxycholesterol (7-keto-25-OHC), a oxysterol, is a Smoothened (Smo) activator. 7-keto-25-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo .
Cat. No.: HY-400897
CAS No.: 1326612-12-7
Research Areas:
7α,25-Dihydroxycholesterol intermediate-1 is an intermediate in the synthesis of 7α,25-Dihydroxycholesterol (HY-113962). 7α,25-Dihydroxycholesterol (7α,25-OHC) can be used as a ligand to target the orphan GPCR receptor EBI2 (GPR183). body, used to synthesize the corresponding PROTEACs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
