64907-23-9
Chemical Structure
7-keto-25-Hydroxycholesterol
Synonym(s): 7-keto-25-OHC
- CAS No.: 64907-23-9
- Formula:C27H44O3
- Molecular Weight:416.64
IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-17-((R)-6-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-1,2,3,4,8,9,10,11,12,13,14,15,16,17-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
InChIKey: NQBVGGWSAXBLBE-BYJKJZODSA-N
SMILES: CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])C(C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Biological Activity: 7-keto-25-Hydroxycholesterol (7-keto-25-OHC), a oxysterol, is a Smoothened (Smo) activator. 7-keto-25-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo[1].
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7-keto-25-Hydroxycholesterol | 7-keto-25-Hydroxycholesterol (7-keto-25-OHC), a oxysterol, is a Smoothened (Smo) activator. 7-keto-25-Hydroxycholesterol binds to the extracellular cysteine-rich domain (CRD) of Smo. | |||||||||||||||||||||
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Keywords
