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Cat. No.: HY-113134R

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25-Hydroxycholesterol (Standard)

(Synonyms: 25-OHC (Standard))

25-Hydroxycholesterol (Standard) is the analytical standard of 25-Hydroxycholesterol. This product is intended for research and analytical applications. 25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.

For research use only. We do not sell to patients.

CAS No.: 2140-46-7
Formula: C₂₇H₄₆O₂
Molecular Weight:402.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

25-Hydroxycholesterol (Standard) Chemical Structure

CAS No.: 2140-46-7

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Sample (0.1mg)

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(In Japan)

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Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2140-46-7
Molecular Weight 402.65
Formula C₂₇H₄₆O₂
SMILES

CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Synonyms

25-OHC (Standard)
Structure Classification
- Steroids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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