1 Result for "

2503096-50-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2503096-50-0" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-149007
CAS No.: 2503096-50-0
Purity:  98.30%
Target:  

STAT Apoptosis

Research Areas:  

Cancer

STAT3-IN-11 (7a) is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes (Survivin and Mcl-1) without affecting its upstream tyrosine kinases (Src and JAK2) levels and p-STAT1 expression. STAT3-IN-11 can induce cancer cell apoptosis, which is potential for the discovery of effective STAT3 inhibitors and antitumor agents against cancers .
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