1 Result for "

2543624-91-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2543624-91-3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-147785
CAS No.: 2543624-91-3
Research Areas:  

Cancer

Pim-1 kinase inhibitor 2 is a PIM-1 kinase inhibitor with a human IC50 of 0.63 μM. Pim-1 kinase inhibitor 2 exhibits high selectivity for cancer cells over normal cells. Pim-1 kinase inhibitor 2 induces apoptosis, increases active caspase-3 levels, upregulates BAX, downregulates Bcl-2, and elevates the Bax/Bcl-2 ratio. Pim-1 kinase inhibitor 2 suppresses cancer cell proliferation and induces cell cycle arrest. Pim-1 kinase inhibitor 2 can be used for the research of prostate carcinoma, hepatocellular carcinoma, and breast adenocarcinoma .
loading...
    loading...