1 Result for "

2568842-26-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2568842-26-0" in MCE Product Catalog:

Cat. No.: HY-155746
CAS No.: 2568842-26-0
Target:  

JAK STAT Akt Apoptosis

Research Areas:  

Cancer

JAK2-IN-9 is an orally active selective JAK2 inhibitor with a human IC50 of 5 nM. JAK2-IN-9 inhibits JAK2 kinase activity, blocks JAK2 phosphorylation, and suppresses the activation of the downstream JAK2-STAT signaling pathway. JAK2-IN-9 inhibits the phosphorylation of STAT3, STAT5 and AKT in cancer cells. JAK2-IN-9 induces cancer cell apoptosis (apoptosis) and cell cycle arrest. JAK2-IN-9 can be used for the research of myeloproliferative neoplasms .
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