JAK2-IN-9
JAK2-IN-9 (Compound A8) is a selective JAK2 inhibitor (IC50: 5 nM). JAK2-IN-9 inhibits the phosphorylation of JAK2, STAT3, and STAT5. JAK2-IN-9 has metabolic stabilities. JAK2-IN-9 induces apoptosis. JAK2-IN-9 can be used for research of myeloproliferative neoplasms (MPNs).
For research use only. We do not sell to patients.
- CAS No.: 2568842-26-0
- Formula: C20H24N6O2S
- Molecular Weight:412.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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JAK2 |
Chemical Information
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CAS No. 2568842-26-0
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Molecular Weight 412.51
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Formula C20H24N6O2S
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SMILES
C=CS(=O)(NCC1=CC=C(NC2=NC=C(C)C(C3=CN(C(C)C)N=C3)=N2)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)