1 Result for "

261766-23-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "261766-23-8" in MCE Product Catalog:

Cat. No.: HY-135081
CAS No.: 261766-23-8
Synonyms: N-4AIA
Target:  

COX

Research Areas:  

Others

N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.1 N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 μM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.
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