1 Result for "

2635386-55-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2635386-55-7" in MCE Product Catalog:

Cat. No.: HY-180981
CAS No.: 2635386-55-7
Target:  

PROTACs Bcr-Abl

Research Areas:  

Cancer

P19As is a BCR-ABL PROTAC degrader based on Asciminib (HY-104010), with a DC50 value of approximately 200 nM for the wild-type BCR-ABL protein. P19As can degrade the T315I mutant and exhibits potent anti-proliferative activity in BaF3-BCR-ABL (T315I) cells. P19As can be used for the study of chronic myeloid leukemia and acute lymphoblastic leukemia .
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