1 Result for "

2700035-54-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2700035-54-5" in MCE Product Catalog:

Cat. No.: HY-144694
CAS No.: 2700035-54-5
Target:  

HSP HDAC Fungal

Research Areas:  

Infection

HDAC/HSP90-IN-3 (compound J5) is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 μM, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1 .
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