1 Result for "

2757991-65-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2757991-65-2" in MCE Product Catalog:

Cat. No.: HY-143236
CAS No.: 2757991-65-2
Target:  

Bacterial Fungal

Research Areas:  

Infection

DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249 .
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