DHFR-IN-1
DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249.
For research use only. We do not sell to patients.
- CAS No.: 2757991-65-2
- Formula: C22H22N6O4S2
- Molecular Weight:498.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 40.71 ± 1.86 nM (DHFR)[1]
Chemical Information
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CAS No. 2757991-65-2
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Molecular Weight 498.58
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Formula C22H22N6O4S2
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SMILES
CN1CCN(CC1)S(=O)(C2=CC=C3NC(/C(C3=C2)=N\NC4=NC(C5=CC=C(C=C5)O)=CS4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DHFR-IN-1 Related Classifications
HY-143236 Related Classifications
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