1 Result for "

2760970-10-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2760970-10-1" in MCE Product Catalog:

Cat. No.: HY-143881
CAS No.: 2760970-10-1
Target:  

FGFR

Research Areas:  

Cancer

FGFR4-IN-6 (Compound 9ka) is a covalently reversible FGFR4 inhibitor with an IC50 value of 5.4 nM. FGFR4-IN-6 also exhibits good oral pharmacokinetic properties. FGFR4-IN-6 induces significant tumor regressions in a xenograft mouse model of Hep3B2.1-7 HCC cell line without an obvious sign of toxicity . FGFR4-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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