1 Result for "

2768472-28-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2768472-28-0" in MCE Product Catalog:

Cat. No.: HY-144605
CAS No.: 2768472-28-0
Purity:  97.39%
Target:  

EGFR PROTACs

Research Areas:  

Cancer

PROTAC EGFR degrader 3 is a selective EGFR mutant PROTAC degrader with activity against EGFR L858R/T790M and EGFR del19, with DC50 values of 1.56 nM and 0.49 nM, respectively. PROTAC EGFR degrader 3 induces degradation via formation of a ternary complex with VHL, ubiquitination, and lysosomal processing. PROTAC EGFR degrader 3 inhibits tumor cell proliferation. PROTAC EGFR degrader 3 can be used for the research of non-small cell lung cancer .
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