1 Result for "

2824131-20-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2824131-20-4" in MCE Product Catalog:

Cat. No.: HY-144098
CAS No.: 2824131-20-4
Target:  

Parasite HDAC

Research Areas:  

Others

HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs .
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