1 Result for "

2918762-17-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2918762-17-9" in MCE Product Catalog:

Cat. No.: HY-186021
CAS No.: 2918762-17-9
Target:  

PROTACs YAP

Research Areas:  

Cancer

PROTAC TEAD degrader-2 (Compound 31) is an efficient TEAD1 PROTAC degrader with a DC50 of 0.6 nM. PROTAC TEAD degrader-2 inhibits the YAP/TAZ-TEAD interaction, with a IC50 of 1.8 nM. PROTAC TEAD degrader-2 exhibits significant selective inhibitory activity against YAP-dependent cancer cells and effectively suppresses the transcriptional activity mediated by YAP. PROTAC TEAD degrader-2 can be used for research on mesothelioma and glioma .
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