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2918764-16-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2918764-16-4" in MCE Product Catalog:

Cat. No.: HY-157404
CAS No.: 2918764-16-4
Target:  

Pim

Research Areas:  

Cancer

Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive PIM-1 and PIM-2 kinase inhibitor with IC50s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines .
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