1 Result for "

2929223-35-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2929223-35-6" in MCE Product Catalog:

Cat. No.: HY-168534
CAS No.: 2929223-35-6
Target:  

SF3B1 Apoptosis FOXA

Research Areas:  

Cancer

WX-02-23 is a small-molecule probe that stereoselectively and site-specifically binds to C258 of FOXA1 and C1111 of SF3B1. WX-02-23 remodels FOXA1's chromatin binding and pioneer activity in a DNA-dependent manner, disrupts spliceosome assembly, and enhances the thermal stability of SF3B1. WX-02-23 inhibits tumor cell proliferation and induces apoptosis. WX-02-23 can be used for research on cancers such as prostate cancer .
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