1 Result for "

2971782-73-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2971782-73-5" in MCE Product Catalog:

Cat. No.: HY-155760
CAS No.: 2971782-73-5
Research Areas:  

Cancer

hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide and a potential dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. hCA/VEGFR-2-IN-3 inhibits VEGFR-2 (IC50=358 nM), has high binding activity to hCAs with Ki of 4.2 nM (hCA IX), 22.9 nM (hCA II), 25.1 nM (hCA I), 28.0 nM (hCA XII), respectively. hCA/VEGFR-2-IN-3 has antiproliferative activity against VEGFR-2 overexpressing breast cancer cells .
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