1 Result for "

299157-43-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "299157-43-0" in MCE Product Catalog:

Cat. No.: HY-P5352
CAS No.: 299157-43-0
Target:  

CD44

Research Areas:  

Inflammation/Immunology Cancer

Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a Kd value of 1.65 μM. Hyaluronan-IN-1 blocks CD44-dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma .
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