1 Result for "

3002409-47-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3002409-47-1" in MCE Product Catalog:

Cat. No.: HY-172732
CAS No.: 3002409-47-1
Research Areas:  

Cancer

PRMT5-IN-50 is an orally active and selective inhibitor of PRMT5. PRMT5-IN-50 has good metabolic stability and low clearance rate in human liver microsomes. PRMT5-IN-50 inhibits SDMA/HCT116-MTAPdel and SDMA/HCT116-MTAPwt with IC50s value of 1.0, 536 nM for arginine symmetric methylation, 19, 1620 nM for anti-proliferation, respectively. PRMT5-IN-50 inhibits tumor growth in mice .
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