1 Result for "

3018914-66-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3018914-66-1" in MCE Product Catalog:

Cat. No.: HY-156292
CAS No.: 3018914-66-1
Research Areas:  

Cancer

IHMT-EZH2-426 is an orally active and selective EZH2 degrader. IHMT-EZH2-426 forms a covalent bond with Cys663 of EZH2, inhibits its catalytic activity, and reduces the protein levels of EZH2 as well as the level of H3K27me3. IHMT-EZH2-426 acts as an antiproliferative agent against B-cell lymphoma and triple-negative breast cancer cells, and also exhibits anti-tumor related activity in Pfeiffer and MDA‑MB‑231 xenograft models. IHMT-EZH2-426 can be used in studies related to B-cell lymphoma and triple-negative breast cancer .
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