1 Result for "

3025799-28-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3025799-28-1" in MCE Product Catalog:

Cat. No.: HY-170919
CAS No.: 3025799-28-1
Target:  

FGFR

Research Areas:  

Cancer

FGFR2/3-IN-2 (compound 10) is an orally active FGFR2 and FGFR3 inhibitor. FGFR2/3-IN-2 inhibits FGFR2 and FGFR3 with IC50s of 3.7 nM and 31.2 nM (preincubation time 1 h), respectively. FGFR2/3-IN-2 spares FGFR1/4 and other kinases without causing diarrhea and serum phosphate elevation in vivo. FGFR2/3-IN-2 induces tumor stasis or regression in the SNU-16 gastric cancer model .
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