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FGFR2/3-IN-2

FGFR2/3-IN-2 (compound 10) is an orally active FGFR2 and FGFR3 inhibitor. FGFR2/3-IN-2 inhibits FGFR2 and FGFR3 with IC50s of 3.7 nM and 31.2 nM (preincubation time 1 h), respectively. FGFR2/3-IN-2 spares FGFR1/4 and other kinases without causing diarrhea and serum phosphate elevation in vivo. FGFR2/3-IN-2 induces tumor stasis or regression in the SNU-16 gastric cancer model.

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  • CAS No.: 3025799-28-1
  • Formula: C29H23FN6O3
  • Molecular Weight:522.53
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FGFR2/3-IN-2 Chemical Structure
    FGFR2/3-IN-2 Chemical Structure
CAS No.: 3025799-28-1
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  • FGFR2/3-IN-2 Chemical Structure
    FGFR2/3-IN-2 Chemical Structure
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  • FGFR2/3-IN-2