1 Result for "

3033586-50-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3033586-50-1" in MCE Product Catalog:

Cat. No.: HY-170343
CAS No.: 3033586-50-1
Target:  

PROTACs SWI/SNF Complex

Research Areas:  

Cancer

PROTAC SMARCA2 degrader-32 is a potent, selective SMARCA2 PROTAC degrader, with DC50 values of 1.3 nM and 94 nM against SMARCA2 and SMARCA4, respectively. PROTAC SMARCA2 degrader-32 exhibits IC50 against SMARCA2, SMARCA4 and the VHL E3 ubiquitin ligase of 30 nM, 63 nM and 25 nM, respectively. PROTAC SMARCA2 degrader-32 inhibits the growth of SMARCA4-deficient cancer cells. It can be used in research on cancers such as fibrosarcoma .
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