PROTAC SMARCA2 degrader-32
PROTAC SMARCA2 degrader-32 (Compound 27) is the degrader for SMARCA2 with a DC50 of 1.3 nM. PROTAC SMARCA2 degrader-32 inhibits the proliferation of lung cancer cell NCI-H838 with a GI50 of 34 nM.
(Pink: SMARCA2 ligand (HY-170349); Blue: VHL ligand (HY-170348); Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3033586-50-1
- Fòrmula: C54H64ClN9O4S
- Peso molecular:970.66
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 3033586-50-1
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Peso molecular 970.66
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Fòrmula C54H64ClN9O4S
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SMILES
CC1(C(N(C2=CC=CC(Cl)=C23)C4=CC(C5CCN(CC5)C[C@@H]6CC[C@@H](C7=CN(N=N7)[C@@H](C(C)(C)C)C(N8[C@@H](C[C@H](C8)O)C(N[C@H](C9=CC=C(C%10=C(N=CS%10)C)C=C9)C)=O)=O)CC6)=CC=C41)=NC3=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC SMARCA2 degrader-32 Related Classifications
HY-170343 Related Classifications
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