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Cat. No.: HY-170349

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SMARCA2 ligand-11

SMARCA2 ligand-11 is the ligand for SMARCA2, and can be used for synthesis of PROTAC SMARCA2 degrader-32 (HY-170343) as ligand for target protein.

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CAS No.: 3033592-44-5
Formule: C₂₂H₂₂ClN₃O
Masse moléculaire:379.88

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

SMARCA2 ligand-11 Chemical Structure

CAS No.: 3033592-44-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Description

SMARCA2 ligand-11 is the ligand for SMARCA2, and can be used for synthesis of PROTAC SMARCA2 degrader-32 (HY-170343) as ligand for target protein^[1].

IC₅₀ & Target

SMARCA2

Voir tous les produits spécifiques à Isoform SWI/SNF Complex :

Chemical Information

CAS No. 3033592-44-5
Masse moléculaire 379.88
Formule C₂₂H₂₂ClN₃O
SMILES

O=C1N=C2N(C3=CC(C4CCNCC4)=CC=C3C2(C)C)C5=C1C(Cl)=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Li Z, et al., Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders. J Med Chem. 2024 Nov 21. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
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SMARCA2 ligand-11

Voir tous les produits spécifiques à Isoform SWI/SNF Complex

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SMARCA2 ligand-11 Related Classifications

HY-170349 Related Classifications