(S)-(S,R,S,R)-AHPC-Me-N3
Based on 1 Customer Validation
(S)-(S,R,S,R)-AHPC-Me-N3 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-32 (HY-170343) and can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 95.0%
- CAS No.: 2958620-43-2
- Formula: C23H30N6O3S
- Molecular Weight:470.59
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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VHL |
Chemical Information
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CAS No. 2958620-43-2
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Appearance Solid
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Molecular Weight 470.59
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Formula C23H30N6O3S
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Color White to off-white
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SMILES
O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)N=[N+]=[N-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (53.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (558 KB)
- English - EN (558 KB)
- Français - FR (558 KB)
- Deutsch - DE (558 KB)
- Norwegian - NO (558 KB)
- Español - ES (558 KB)
- Swedish - SV (558 KB)
- Italian - IT (558 KB)
- Korean - KR (558 KB)
- Portuguese - PT (558 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.1250 mL | 10.6250 mL | 21.2499 mL | 53.1248 mL |
| 5 mM | 0.4250 mL | 2.1250 mL | 4.2500 mL | 10.6250 mL | |
| 10 mM | 0.2125 mL | 1.0625 mL | 2.1250 mL | 5.3125 mL | |
| 15 mM | 0.1417 mL | 0.7083 mL | 1.4167 mL | 3.5417 mL | |
| 20 mM | 0.1062 mL | 0.5312 mL | 1.0625 mL | 2.6562 mL | |
| 25 mM | 0.0850 mL | 0.4250 mL | 0.8500 mL | 2.1250 mL | |
| 30 mM | 0.0708 mL | 0.3542 mL | 0.7083 mL | 1.7708 mL | |
| 40 mM | 0.0531 mL | 0.2656 mL | 0.5312 mL | 1.3281 mL | |
| 50 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0625 mL |
(S)-(S,R,S,R)-AHPC-Me-N3 Related Classifications
HY-170348 Related Classifications
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